27.11.2025
Reading time:
10 minutes

PIOL

PiOL — safe vision correction when laser eye surgery is not possible

Dr. Valery Vinzent Wittwer
indications

Gold standard for correcting larger ametropies
Indication to correct minor and moderate ametropia only if:

  • Schirmer test < 5 mm, fluorescein staining of epithelial lesions of the cornea or conjunctiva
  • thin cornea < 480 um
  • irregular topography (inferior steepening > 1.5 D, posterior float > 14 um, etc.)
  • Scars in the Area of Corneal Stroma
  • Martial Arts, Police

Scope of application for PIOLs
(Information provided by manufacturers)

  • Myopia from -6 dpt (from -1)
  • Farsightedness from +3 dpt (from +1)
  • Astigmatism from 5 dpt (from 1)
  • Age > 18 years
  • Stable eyeglass values (<0.5 dpt. for 6-12 months)
  • No pregnancy/ breast-feeding
Contraindications
  • Cataract or glaucoma
  • Inflammatory eye diseases (e.g. uveitis)
  • Endoth cell density < 2000/mm2
  • Internal anterior chamber depth (endothelium to front lens surface)
    • Myopia < 2.8 mm
    • hyperopia < 3.0 mm for hyperopia)
  • Pregnancy, breast-feeding
    • Possible 3 months after weaning

Preparation

  • Topography/tomography (Pentacam®)
  • White to white (Pentacam®)
  • Biometrics (Pntacam®)
  • ICL® /IPCL® calculation by opticians
  • OCT M P and photos (for documentation)
  • corneal endothelial mirror microscopy (for documentation)
  • Information -> see PIOL consent form (i.B. pain/inability to work at least 1-2 days, up to 4 weeks)
    • UP to 100% possible for 2 weeks in case of illness (CL intolerance, skin scar, etc.)
  • Preoperative preparation
    • Yellox Eye Drops 2x/D/Nevanac 3mg 1x/Day/Nevanac 1mt 3x/day for 5 days until surgery
    • Oxybuprocaine 0.4% SDU eye drops 3x every 5 minutes

Edit surgical material

  • Prepare a sterile operating room
  • Undiluted hibidil solution/povidone iol solution 5-10%
  • 6x round swab
  • BSS solution
  • Large ICL® clip and packaging to open
  • incisions
    • 1.2 mm
    • 2.4 mm
  • Lidocaine 1.0%
  • viscoelastic discursive (e.g. HPMC 2%)
  • ICL® manipulator/spatula
  • I/A
  • Shooter
    • ICL® green/yellow from Mediconsult
    • IPCL® /ICL® blue/white 2.4 mm
  • Dreieckstupfer
  • Miostat® solution
  • Aprokam® solution
  • BSS solution

Operation process

See Operation Report

Post-operative therapy

  • prophylaxis
    • Tobradex® eye drops every hour until the first follow-up
    • Diamox 250 mg Tbl 1x immediately after surgery 1x at night 1x the next morning
  • Analgesia when needed
    • Dafalgan 500mg Tbl 4x/day to 8x/day
      (Cave: Total 4g/day only if no alcoholism or liver problems are known)
    • Mefenacid 500mg Tbl 3x/day

Post-operative procedure

  • 1 day: Follow-up
    • Therapy: Tobradex® eye drops 4x/day, Yellox eye drops 2x/day procedure: Control in 1 week with Autoref (no vision check) and anterior segment OCT, Optava eye drops for moisturizing as needed control in approximately 7 days with Autoref (no visual check)
    • Test module “ICL1"
      OX 1 day after ICL/IPCL implantation
      Previous bulb sections
      Conjunctiva: easily injected
      Cornea: smooth, clear
      Anterior chamber: deep, irritant
      IRIS/Pupil: round, plays, medical miosis, ICL/ IPCL in loco, right centered
      Natural lens clear
      Fd: central retina unobtrusive
      Anterior segment OCT (OCT front section settled): Vault XXX μm
      Therapy: Tobradex® eye drops 4x/day, Yellox eye drops 2x/day
      Procedure: Inspection in 1 week with autorefractometer (no visual inspection) and anterior segment OCT
    • cave:
      • Always applanatory tonomtria
      • PIoL and distance from the natural lens (vault) must be visible
      • Vault should be between 250-700 um (may change in the first few days to weeks)
  • 1 week
    • Substantiate Therapy as After Cataract Surgery, Anterior Segment OCT
  • 1 month
    • Snuff out therapy, anterior segment OCT and endothelial cells
  • 1 year
    • Anterior segment OCT and corneal endothelium mirror microscopy
    • Examination of peripheral retina in mydriasis (only in patients with myopia of > 6 diopters, peripheral retinal degeneration or retinal symptoms) -> also draw the patient's attention to the symptoms of vitreous dissection

miscellaneous

  • If there is increased cell irritation or fibrin accumulation without pain on the first postoperative day -> suspicion of TASS (Toxic Anterior Segment Syndrome)
    • Increasing topical steroids and close follow-up
      • Early treatment improves prognosis
      • Can take several days until the cornea completely clears
      • Cave: Differential diagnosis of endophthalmitis
  • Visual acuity may take a few days (e.g. in the case of post-operative corneal edema)
  • Post-correction as a touch-up with PRK/Transprk/LASIK after at least 6 months with stable topography

sources

  • CRC guidelines 2024
  • Information from manufacturers (ICL®, IPCL®)

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